There’s Toxicity, and There’s Toxicity (2017)
A baby-aspirin-size amount of powdered toxin is enough to make the global supply of Botox for a year. Occasionally, some of the toxin is shipped in secrecy to the lab in Irvine for research. Even less frequently, a bit of the toxin is transported by private jet, with guards aboard, to the plant in Ireland. In the non-venom protein toxin world, the most well-known is ricin, but that's another case where the definitions get tricky. At their worst, ricin toxins are down in the single-digit microgram/kilo range, which is very bad. There are many others in this group, which normally would be considered very dangerous indeed, but not when you're competing with ricin and botulinum. In general, small molecules can't quite get down to those levels of toxicity. There may be some marine toxins that beat these, but in general, I don't think that small molecules can compete with the true horrors.