An Organocatalysis Nobel

# · ✸ 22 · 💬 2 · 14 days ago · www.science.org · IMAYousaf
The more simple lipids don't have any chiral centers in them, but ones with branched structures can. Ibuprofen has one chiral carbon in its structure, for example, and that's all you need - amphetamine is the same way. A structure with two chiral centers can have four isomers, and one with three can have eight. There has to be a chiral starting material or reagent involved somewhere, or there's nothing to distinguish a right-handed product from a left-handed one. You can use a chiral reagent of some sort, perhaps even sticking a whole chiral piece reversibly onto your molecule of interest to influence the chemistry. The key is that their chiral compounds come in and make transient intermediate structures with the reactants, and are then released to start the whole process over again. That's because there are a great number of possible structures one could imagine using for the chiral catalytic species, and there are a great many ways to use them.
An Organocatalysis Nobel



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